Holders Kumasi Asante Kotoko have been paired with Division One League campaigners Asokwa Deportivo in the Round of 16 of the MTN FA Cup.
The Porcupine Warriors advanced to the next stage after beating third tier side Thunderbolts FC 3-1 at the Okese Park, Ejisu in the Round of 32.
Meanwhile, record holders Accra Hearts of Oak will play Accra Young Wise after eliminating Windy Professionals.
The rainbow club is on course for a double this campaign after tightening their lead on top of the GPL Table with an impressive win 1-0 over archrivals Kotoko.
Two time winners Medeama SC will face Accra Great Olympics in a battle of former champions. Great Olympics have been champions three times (1975, 1983, 1995) – and would see this as a golden opportunity to win a trophy this term to round up a stellar campaign.
MTN FA Cup Round 16 draw: Full Draw
Aduana Stars v Ashanti Gold SC
Asante Kotoko v Asokwa Deportivo
Kintampo v Berekum Chelsea
Kintampo Top Talents v Tamale City
Young Wise v Hearts of Oak
Attram v Legon Cities
Medeama SC v Great Olympics
Elmina Sharks v Tema Youth